Generation of a color coded particle library for use in multiplex immunoassays

Abstract

Even though we live in a world characterized by perpetual medical and technological advances, 8 out of every 10 people worldwide lack the ability to have their health problems diagnosed and often suffer and die even though cures to their illness are known. The fundamental research discussed here targets the preliminary development of a color coded colloidal particle library to be used later in bio-affinity arrays capable of multiplex immunoassays where they will be fluorescently tagged to a certain protein so they can be used to diagnosis of a disease. To fully accomplish this goal the most efficient procedures need to be made for the dye solutions used to color the particles and method to dye the particles, so dyed, non-fluorescent, polystyrene (PS) particles can be obtained.