Expression Analysis of the MBP1 Gene in Candida albicans

Abstract

Candida albicansis the most commonly isolated fungal pathogen in humans. Candida albicansis a dimorphic species, having both single-celled (the yeast form) and filamentous growth forms. Morphogenesis, the ability to transition from the yeast state to the filamentous morphology, has been identified as an important factor in causing systemic infections. Environmental factors that regulate morphological conversions include pH, temperature, the presence or absence of serum, and the availability of nitrogen. Our research then set out to determine whether the Mbp1 protein is constitutively expressed or differentially expressed according to environmental signals.