Importance of CCW12 gene expression in zinc deficient Saccharomyces cerevisiae
| dc.contributor.advisor | Eide, David | |
| dc.contributor.author | Mateo, Michael | |
| dc.date.accessioned | 2007-09-12T14:55:49Z | |
| dc.date.available | 2007-09-12T14:55:49Z | |
| dc.date.issued | 2007 | |
| dc.description | 17 p. | en |
| dc.description.abstract | Pathogenic fungi have a major impact on human health. There is a lack of good therapies and some pathogenic fungi are resistant to the existing treatments. One possible target for treatment is covalently bonded cell wall protein 12 (CCW12), which is a cell wall protein that is needed for structural stability of the fungal cell wall. CCW12 is also induced in low zinc conditions by Zap1, which is a protein that is involved in transcriptional regulation in response to zinc. The goal of this study was to determine why CCW12 is up-regulated in low zinc conditions by Zap1. A number of experiments were conducted and seem to indicate that the CCW12 is up-regulated in low zinc to help stabilize the cell wall. More studies should be done to clarify the role of CCW12 and to investigate possible treatment for fungal infections. | en |
| dc.format.extent | 174416 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://digital.library.wisc.edu/1793/18285 | |
| dc.language.iso | en_US | en |
| dc.subject | Nutritional Sciences | en |
| dc.title | Importance of CCW12 gene expression in zinc deficient Saccharomyces cerevisiae | en |
| dc.type | Thesis | en |