Energetics of Hydride Transfer Reactions in Quinone Reductase 2
| dc.contributor.advisor | Hati, Sanchita | |
| dc.contributor.advisor | Bhattacharyya, Sudeep | |
| dc.contributor.author | Yang, Yer | |
| dc.contributor.author | Bartholow, Thomas G. | |
| dc.contributor.author | North, Michael A. | |
| dc.date.accessioned | 2012-10-03T19:23:59Z | |
| dc.date.available | 2012-10-03T19:23:59Z | |
| dc.date.issued | 2012-04 | |
| dc.description | Color poster with text, images, diagrams, charts, graphs, and tables. | en |
| dc.description.abstract | Quinone Reductases belong to the class of flavin-dependent oxidoreductases. With its redox active cofactor flavin adenine dinucleotide (FAD), quinone reductases are known to utilize a ping pong kinetic mechanism during catalysis in which a hydride is swapped back and forth between flavin and its two substrates. The objectives of this study were: to explore the energetics of the ping pong kinetics in NQO2; to examine the conformational changes and free energy change due to substrate shuttling; and to determine the best functional to calculate the electron interaction. | en |
| dc.description.sponsorship | University of Wisconsin--Eau Claire Office of Research and Sponsored Programs. | en |
| dc.identifier.uri | http://digital.library.wisc.edu/1793/63156 | |
| dc.language.iso | en_US | en |
| dc.relation.ispartofseries | USGZE AS589 | en |
| dc.subject | Chemical kinetics | en |
| dc.subject | Quinone | en |
| dc.subject | Flavins | en |
| dc.subject | Oxidoreductases | en |
| dc.subject | Posters | en |
| dc.title | Energetics of Hydride Transfer Reactions in Quinone Reductase 2 | en |
| dc.type | Presentation | en |