Testing D1 dopamine receptors and glutamate combined effects on brain stimulation reward in the extended amygdala

dc.contributor.advisorWaraczynski., Meg
dc.contributor.authorStoehr, Michele
dc.date.accessioned2012-07-05T15:39:27Z
dc.date.available2012-07-05T15:39:27Z
dc.date.issued2012
dc.descriptionThis file was last viewed in Adobe Reader Xen
dc.description.abstractPurpose: To further understand the neural mechanisms underlying evaluation of rewarding stimuli in the mammalian brain. More specifically, to examine the effects of dopamine and glutamate manipulations in the central aspect of the sublenticular extended amygdala (SLEAc) on reward evaluation. Dopamine (DA) and glutamate (GLU) interact and are involved in reward evaluation. Our lab found a decrease in reward value when dopamine receptor 2 (D2) agonist/glutamate blocker combination solution was microinjected into the SLEAc but not the nucleus accumbens shell. Similar research suggests this effect may be more pronounced if dopamine receptor 1 (D1) drugs rather than D2 drugs are microinjected with GLU drugs.en
dc.identifier.urihttp://digital.library.wisc.edu/1793/61636
dc.language.isoen_USen
dc.subjectNeurotransmitter receptorsen
dc.subjectDopamineen
dc.subjectGlutamic aciden
dc.subjectBrain stimulationen
dc.subjectAmygdaloid bodyen
dc.subjectBrainen
dc.titleTesting D1 dopamine receptors and glutamate combined effects on brain stimulation reward in the extended amygdalaen
dc.typePresentationen

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