Effects of Chlorpromazine in Rats Trained to Discriminate Between 2 and 22 Hr Food Deprivation
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Dobbe, Jennifer E.
Donovan, Bryan A.
Hoida, Emily J.
Franklin, Bethany R.
Gomer, Bailey
Johnson, Amy R.
Michener, M.J.
Nelson, Courtney L.M.
Reed, Krystal A.
Van Asten, Ryan M.
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Abstract
Chlorpromazine, a typical antipsychotic, has been shown to have varying effects on food intake. Chlorpromazine is a dopamine antagonist
that blocks several dopamine receptors (including D1 and D2). Previous research indicated chlorpromazine (5.0mg/kg) may affect food intake in two time phases. This study looked at the effects of chlorpromazine in a food-deprivation discrimination paradigm that may serve as an animal model of 'hunger'.
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Color poster with text, graphs, and tables.
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University of Wisconsin--Eau Claire Office of Research and Sponsored Programs.