MBP1 Null Mutant Strains of Candida albicans Do Not Show Defects in Responding to Oxidative Stress.

Abstract

Candida albicans is the most frequently isolated fungal pathogen in humans. Morphogenesis, the transition from a yeast to filamentous morphology, has been demonstrated to play an important role in the organism's ability to cause systemic disease. To further characterize the role of the Mbp1 protein in C. albicans, we tested the survival of wild-type, heterozygous, and null mutant strains in the prescence of various peroxides.