Comparison of Coarse-Grained and Atomistic-Level Simulations for Aminoacyl-tRNA Synthetases
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Strom, Alexander M.
Tadayon, Stephanie N.
Yang, Yer
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Aminoacyl-tRNA synthetases (AARSs) are a group of multi-domain enzymes responsible for catalyzing the covalent attachment of an amino acid to the cognate tRNA forming an aminoacyl-tRNA. In this study, both atomistic-level and coarse-grained dynamic simulations were conducted on Escherichia coli methionyl-tRNA synthetase (Ec MetRS), Enterococcus faecalis prolyl-tRNA synthetase (Ef ProRS), and Thermus Thermophilus leucyl-tRNA synthetase (Tt LeuRS).
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Color poster with text, diagrams, charts, images, and tables.
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University of Wisconsin--Eau Claire Office of Research and Sponsored Programs; National Institute of Health; National Science Foundation through TeraGrid Resources.