Efforts to establish a GFP-ERV env expression vector using trophoblast cell cultures as target gene source.

dc.contributor.authorSchimmel, Sarah
dc.contributor.authorLyden, Timothy
dc.date.accessioned2006-01-20T16:28:25Z
dc.date.available2006-01-20T16:28:25Z
dc.date.issued2005-04
dc.descriptionColor poster with text describing research conducted by Sarah Schimmel and Dr. Timothy Lyden (University of Wisconsin-River Falls) that examines the effort to clone the syncytin gene into an eGFP expression vector for use in studies directed at defining the role and functions of cytoskeletal elements in normal endogenous retroviral mediated cellular fusion.en
dc.description.abstractThe purpose of this project is to clone the envelope gene of human endogenous retrovirus-W (hERV-W) into a commercial GFP containing expression vector. This is being pursued in order to generate a fusion gene for use as a marker in several of our placental studies. This gene, HERV-W was reported and subsequently confirmed to be the protein which mediates developmental cellular fusion in the trophoblast of normal human placenta. Our lab is very interested to construct this vector to aid in studies focused on cytoskeletal changes in the normal placental trophoblast.en
dc.format.extent111212 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.urihttp://digital.library.wisc.edu/1793/343
dc.language.isoen_US
dc.subjectMolecular biologyen
dc.subjectTrophoblasten
dc.subjectTrophoblast cell biologyen
dc.subjectPlacentaen
dc.subjectPlacental studiesen
dc.subjectPlacentologyen
dc.subjectPlacental biologyen
dc.subjectPlacental developmenten
dc.subjectERV provirusen
dc.subjectEndogenous retroviral provirusen
dc.subjectGFP expression vectoren
dc.subjectCytoskeletal changesen
dc.subjectCell biologyen
dc.subjectCloningen
dc.titleEfforts to establish a GFP-ERV env expression vector using trophoblast cell cultures as target gene source.en
dc.typeImageen

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