The Impact of Pretreatment Time on the Ability to Discriminate Haloperidol From Saline in Rats with Chronic Sucrose Access
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Jewett, David C.
Gorres, Kaci
Tryhus, Aaron M.
Rothbauer, Dylan
Marek, Morgan A.
Barton, Allison
Brandt, Lucas J.
Schulz, Emily
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Previous research has shown an increase in dopamine (DA) functioning following chronic, intermittent sucrose consumption. McElroy (1989) was able to train rats to discriminate haloperidol (HAL; a D2 antagonist; 0.05 mg/kg i.p.) in a mean of 45 training sessions. This discrimination was established without chronic sucrose consumption. Since chronic, intermittent sucrose consumption increases DA function, we were led to believe that the consumption could cause the discrimination to be acquired more quickly.
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Color poster with text, graphs, and charts.
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The University of Wisconsin-Eau Claire Summer Research Experiences for Undergraduates Grant; The University of Wisconsin-Eau Claire Research and Creative Activity Grant; Student Differential Tuition through the University of Wisconsin- Eau
Claire’s Student Travel for the Presentation of Research Results Program; Minnesota Obesity Center; University of Wisconsin--Eau Claire Office of Research and Sponsored Programs.